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Insulin, to treat type 2 diabetes the pancreas does not produce sufficient insulin and the cells of the body are resistant to the low levels of insulin circulating in the blood. Metformin is used as a first line treatment of type 2 diabetes. Metformin also increases your body's response to insulin, Metformin may decrease the risk of lactic acidosis while you are taking this medicine. Metformin may be used with lifestyle changes such as diet and exercise have failed to control blood sugar levels both between and directly after meals.