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Paroxetine dosage sexual side effect: "This drug must be taken regularly for a few weeks before its full effect is felt. Symptoms of anxiety and depression. Recent studies suggest an increased risk of Paxil birth defects for pregnant women during their first trimester. With depression, the most severe cognitive and behavioral malfunctions are expressed in what is called a major depressive disorder, which is also called clinical depression. Paxil should be taken once a day, either in the morning or evening, with or without food. Paxil has been approved by the FDA to treat depression. Do not take Paxil without first talking to your doctor if you are pregnant or could become pregnant during treatment. Recent studies suggest an increased risk of Paxil birth defects for pregnant women during their first trimester."